Description

tert-Butyl 3-Cyano-2,5-dihydropyrrole-1-carboxylate is a high-value, protected heterocyclic building block essential for modern synthetic chemistry. This compound serves as a versatile intermediate in the construction of complex nitrogen-containing molecular frameworks, offering significant advantages in route design and functional group compatibility. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of pyrrolidine-based drug candidates, including kinase inhibitors, protease inhibitors, and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its functionalized pyrroline core.
• Chemical Research: Serves as a versatile building block in academic and industrial R&D for constructing complex heterocycles and exploring new chemical space.
• Material Science Precursor: Potential use in the development of specialty polymers, ligands for catalysis, and other functional organic materials.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of client-specific target molecules.

Basic Information

Product Name	tert-Butyl 3-Cyano-2,5-dihydropyrrole-1-carboxylate
CAS No.	1353629-54-5
Molecular Formula	C10H14N2O2
Molecular Weight	194.23 g/mol
Synonyms	1-Boc-3-cyano-2,5-dihydro-1H-pyrrole; 3-Cyano-2,5-dihydro-1H-pyrrole-1-carboxylic acid tert-butyl ester; tert-Butyl 3-cyano-3-pyrroline-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-cyano-2,5-dihydro-1H-pyrrole; 3-Cyano-1-N-Boc-2,5-dihydropyrrole; Boc-3-cyano-2,5-dihydro-1H-pyrrole; 1-Boc-3-cyanopyrroline
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Cyano-2,5-dihydropyrrole-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects with material produced under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.