Description

3-Fluoro-5-(Trifluoromethoxy)Benzamide, 97% is a high-purity fluorinated aromatic building block with the CAS registry number 1352999-12-2. This compound is valued for its unique trifluoromethoxy and fluoro substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules in advanced research. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in CNS, oncology, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorine motifs enhance biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing groups.
• Chemical Biology Probes: Employed in the design of fluorinated probes and tags for studying biological mechanisms and protein interactions.
• Custom Synthesis & Scale-Up: An essential building block for contract research and manufacturing organizations (CROs/CMOs) engaged in custom chemical synthesis projects.

Basic Information

Product Name	3-Fluoro-5-(Trifluoromethoxy)Benzamide, 97%
CAS No.	1352999-12-2
Molecular Formula	C8H5F4NO2
Molecular Weight	223.12 g/mol
Synonyms	3-Fluoro-5-(trifluoromethoxy)benzamide; Benzamide, 3-fluoro-5-(trifluoromethoxy)-; 1352999-12-2; 3-Fluoro-5-trifluoromethoxybenzamide; 5-(Trifluoromethoxy)-3-fluorobenzamide; 3-Fluoro-5-(trifluoromethoxy)benzoic acid amide
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Trifluoromethoxy)Benzamide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.