Description

(9H-Fluoren-9-Yl)Methyl Benzoyloxycarbamate is a specialized carbamate derivative used as a key building block and protecting group reagent in advanced organic synthesis. This compound matters for its role in facilitating complex, multi-step reactions, particularly in the synthesis of peptides and other sensitive molecules where selective protection and deprotection are critical. It is primarily needed by research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries engaged in developing novel active pharmaceutical ingredients (APIs) and complex organic compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): Acts as a crucial reagent for the introduction of the Fmoc (9-fluorenylmethoxycarbonyl) protecting group onto amino acids, a standard methodology in peptide manufacturing.
• Solution-Phase Organic Synthesis: Used as a versatile protecting group agent for amines and alcohols in the multi-step synthesis of complex natural products and pharmaceutical intermediates.
• Research & Development: Serves as a fundamental tool in academic and industrial R&D labs for exploring new synthetic pathways and constructing molecular libraries.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for the production of target molecules under Good Manufacturing Practice (GMP) conditions.
• Bioconjugation Chemistry: Facilitates the controlled modification of biomolecules, such as proteins or oligonucleotides, for diagnostic and therapeutic applications.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methyl Benzoyloxycarbamate
CAS No.	1352786-35-6
Molecular Formula	C23H17NO4
Molecular Weight	371.39 g/mol
Synonyms	Fmoc-OSu Benzoyl Derivative; Benzoyloxycarbonyloxy-(9H-fluoren-9-yl)methyl carbamate; N-[(9H-Fluoren-9-ylmethoxy)carbonyloxy]benzamide; Fmoc-OBz; 9-Fluorenylmethyl benzoyloxycarbamate; (9-Fluorenylmethyloxycarbonyloxy)benzoyl amide; Benzoyl Fmoc-carbamate
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methyl Benzoyloxycarbamate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for reproducible synthetic outcomes. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.