Description

2-Fluoro-4-Formylphenylboronic Acidpinacol Ester is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. Its molecular architecture, featuring both a formyl group and a protected boronic acid, makes it a critical reagent for constructing complex molecules via cross-coupling and subsequent functional group transformations. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl structures found in drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific fluorinated aromatic scaffolds.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and semiconductors.
• Chemical Biology Probes: Utilized to create tagged molecules or activity-based probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Fluoro-4-Formylphenylboronic Acidpinacol Ester
CAS No.	1352657-25-0
Molecular Formula	C₁₄H₁₈BFO₃
Molecular Weight	264.10 g/mol
Synonyms	2-Fluoro-4-formylbenzeneboronic acid pinacol ester; (2-Fluoro-4-formylphenyl)boronic acid pinacol ester; 4-Formyl-2-fluorophenylboronic acid pinacol ester; Pinacol (2-fluoro-4-formylphenyl)boronate; 2-Fluoro-4-formylphenyl-Bpin; B-(2-Fluoro-4-formylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 1352657-25-0
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-Formylphenylboronic Acidpinacol Ester is manufactured and analyzed under strict quality management protocols to ensure consistency and high purity for research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.