Description

3-Ethynyloxetan-3-Ol is a high-value, multifunctional oxetane building block featuring both an alkyne and a hydroxyl group on the same carbon atom. This unique structure makes it a critical intermediate for advanced material science and pharmaceutical research, enabling the synthesis of complex polymers and bioactive molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of new Active Pharmaceutical Ingredients (APIs), particularly for click chemistry (CuAAC) applications and prodrug design.
• Polymer & Material Science: Used as a monomer or cross-linking agent to create advanced polymers with tailored properties like enhanced thermal stability, rigidity, or biodegradability.
• Agrochemical Synthesis: Employed in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Materials: Acts as a building block for synthesizing organic electronic materials and liquid crystal compounds.
• Bioconjugation & Probe Development: Utilized in bioconjugation chemistry to attach fluorescent tags, drugs, or other functional groups to biomolecules via its alkyne handle.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new chemical spaces in organic synthesis and medicinal chemistry.

Basic Information

Product Name	3-Ethynyloxetan-3-Ol
CAS No.	1352492-38-6
Molecular Formula	C5H6O2
Molecular Weight	98.10 g/mol
Synonyms	3-Ethynyl-3-hydroxyoxetane; 3-Hydroxy-3-ethynyloxetane; Oxetan-3-ol, 3-ethynyl-; 3-Oxetanol, 3-ethynyl-; 3-Ethynyloxetan-3-ol; Building block 1352492-38-6
EINECS	Contact for details

Quality Control

Our 3-Ethynyloxetan-3-Ol is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.