Description

1-[(4-Bromo-2,6-Difluorophenyl)Carbonyl]Pyrrolidine is a high-purity, advanced pharmaceutical intermediate featuring a unique halogenated aromatic structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting complex disease pathways. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those requiring a difluorophenyl-pyrrolidine scaffold.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Agrochemical Development: Serves as a precursor in the research and production of advanced crop protection chemicals and pesticides.
• Ligand Synthesis: Can be utilized in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological systems and target identification.

Basic Information

Product Name	1-[(4-Bromo-2,6-Difluorophenyl)Carbonyl]Pyrrolidine
CAS No.	1351668-26-2
Molecular Formula	C11H10BrF2NO
Molecular Weight	290.11 g/mol
Synonyms	4-Bromo-2,6-difluoro-N-(pyrrolidin-1-yl)benzamide; 1-[(4-Bromo-2,6-difluorobenzoyl)]pyrrolidine; Pyrrolidine, 1-[(4-bromo-2,6-difluorophenyl)carbonyl]-; 4-Bromo-2,6-difluorobenzoic acid pyrrolidide; N-(Pyrrolidin-1-yl)-4-bromo-2,6-difluorobenzamide
EINECS	Contact for details

Quality Control

Our 1-[(4-Bromo-2,6-Difluorophenyl)Carbonyl]Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.