Description

n-Boc-2-Methoxymethylpiperidine is a high-purity, protected piperidine derivative serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex nitrogen-containing molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in stereoselective reactions to introduce complex piperidine motifs.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Agrochemical Development: Serves as a building block for creating novel pesticides and herbicides with specific biological activity.
• Catalyst & Ligand Synthesis: A precursor for the development of novel chiral catalysts and ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A fundamental component for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	n-Boc-2-Methoxymethylpiperidine
CAS No.	1351094-46-6
Molecular Formula	C12H23NO3
Molecular Weight	229.32 g/mol
Synonyms	1-Boc-2-Methoxymethylpiperidine; tert-Butyl 2-(Methoxymethyl)piperidine-1-carboxylate; 2-(Methoxymethyl)-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester; 1-(tert-Butoxycarbonyl)-2-(methoxymethyl)piperidine; N-Boc-2-Methoxymethylpiperidine; 1-Boc-2-Methoxymethylpiperidine; N-tert-Butoxycarbonyl-2-methoxymethylpiperidine
EINECS	Contact for details

Quality Control

Our n-Boc-2-Methoxymethylpiperidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and commercial applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, enantiomeric excess, and impurity profiles. Our quality commitment aligns with the standards required for pharmaceutical R&D and cGMP manufacturing support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.