Description

(5-Fluoro-1H-Indol-4-Yl)Boronic Acid is a high-purity, heterocyclic boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated indole-based compounds targeting various therapeutic areas.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides by incorporating the 5-fluoroindole scaffold into lead molecules.
• Material Science: Building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where the boronic acid group facilitates polymerization or functionalization.
• Chemical Biology & Probe Development: Employed in synthesizing fluorescent probes or bioconjugation reagents for studying biological systems and diagnostic applications.
• Academic & Contract Research: Vital reagent for method development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.
• Scale-up Process Chemistry: Suitable for process optimization and pilot-scale production of target molecules in kilo-lab and pilot plant settings.

Basic Information

Product Name	(5-Fluoro-1H-Indol-4-Yl)Boronic Acid
CAS No.	1350836-07-5
Molecular Formula	C8H7BBrFNO2
Molecular Weight	243.86 g/mol
Synonyms	4-Borono-5-fluoro-1H-indole; 5-Fluoro-1H-indole-4-boronic acid; (5-Fluoro-4-indolyl)boronic acid; B-(5-Fluoro-1H-indol-4-yl)boronic acid; 5-Fluoroindole-4-boronic acid; 1350836-07-5; AKOS025311317
EINECS	Contact for details

Quality Control

Every batch of (5-Fluoro-1H-Indol-4-Yl)Boronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC), identity confirmation (by 1H/11B/19F NMR and IR), and residual solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0% (Area %)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.