Description

1-Bromo-Cyclopropanecarbonitrile is a versatile and highly functionalized cyclopropane derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a reactive bromine atom and a nitrile group on a strained three-membered ring, makes it an invaluable precursor for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce cyclopropane motifs or functionalize molecules with high precision.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, antiviral agents, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane ring can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Monomer: Employed in the creation of specialty polymers and functional materials, where its bifunctional nature allows for controlled polymerization and cross-linking.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes and tags for studying biological systems and protein interactions.
• General Organic Synthesis: A versatile reagent for ring-opening, cycloaddition, and nucleophilic substitution reactions to access a wide array of nitrile-containing compounds.

Basic Information

Product Name	1-Bromo-Cyclopropanecarbonitrile
CAS No.	1350746-42-7
Molecular Formula	C4H4BrN
Molecular Weight	146.98 g/mol
Synonyms	Cyclopropanecarbonitrile, 1-bromo-; 1-Bromocyclopropanecarbonitrile; (Bromocyclopropyl)carbonitrile; 1-Bromo-1-cyanocyclopropane; Bromocyclopropanecarbonitrile; (1-Bromocyclopropyl)carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-Cyclopropanecarbonitrile is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical applications. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.