Description

4-Ethoxy-2,3,5,6-Tetrafluorostyrene is a specialized fluorinated styrene derivative, a high-value intermediate prized for its unique chemical reactivity and the properties imparted by its fluorine and alkoxy substituents. This compound is critical for synthesizing advanced materials and fine chemicals where enhanced stability, specific electronic characteristics, or tailored surface properties are required. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced polymer industries for applications in medicinal chemistry, crop protection, and specialty resin development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for introducing fluorinated aromatic motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the fluorostyrene core contributes to efficacy and environmental persistence profiles.
• Advanced Polymer Monomer: Acts as a specialty monomer for creating fluorinated polymers and copolymers with enhanced chemical resistance, low surface energy, and improved thermal stability for coatings and high-performance plastics.
• Liquid Crystal & Electronic Materials: Employed in the development of fluorinated components for liquid crystal displays (LCDs) and organic electronic materials due to its influence on dielectric constant and molecular alignment.
• Cross-coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Heck, Suzuki) for constructing complex, fluorinated biaryl structures in discovery chemistry.
• Material Science Research: Utilized in academic and industrial R&D for surface modification, creating self-assembled monolayers (SAMs), and developing novel fluorinated nanomaterials.

Basic Information

Product Name	4-Ethoxy-2,3,5,6-Tetrafluorostyrene
CAS No.	1350637-16-9
Molecular Formula	C10H8F4O
Molecular Weight	220.16 g/mol
Synonyms	1-Ethoxy-2,3,5,6-tetrafluoro-4-vinylbenzene; 2,3,5,6-Tetrafluoro-4-ethoxystyrene; 4-Ethoxy-2,3,5,6-tetrafluoroethenylbenzene; p-Ethoxytetrafluorostyrene; Vinyltetrafluoroanisole; ETFS (abbreviation); 4-Vinyl-1-ethoxy-2,3,5,6-tetrafluorobenzene
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-2,3,5,6-Tetrafluorostyrene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with relevant regulatory frameworks for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Density (at 20°C)	~1.3 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.