Description

tert-Butyl n-[(1R)-Cyclohex-3-En-1-Yl]Carbamate is a chiral, enantiomerically pure building block of significant value in advanced organic synthesis. This compound matters because it provides a protected amine functionality on a stereodefined cyclohexene scaffold, enabling the efficient construction of complex, biologically active molecules. Pharmaceutical and agrochemical research organizations need it for the development of novel active ingredients, particularly where specific stereochemistry is critical for efficacy.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the creation of enantiomerically pure pesticides and herbicides where specific stereochemistry enhances activity and reduces environmental impact.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric hydrogenation and other catalytic transformations.
• Peptidomimetics & Bioactive Molecule Construction: The protected amine and olefin groups are versatile handles for building complex peptide analogs and other bioactive scaffolds.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new synthetic routes to complex natural products.

Basic Information

Product Name	tert-Butyl n-[(1R)-Cyclohex-3-En-1-Yl]Carbamate
CAS No.	1350636-87-1
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	(1R)-3-Cyclohexen-1-amine, N-BOC-; (R)-N-Boc-3-cyclohexen-1-amine; tert-Butyl (1R)-3-cyclohexen-1-ylcarbamate; (R)-tert-Butyl cyclohex-3-en-1-ylcarbamate; (R)-N-(tert-Butoxycarbonyl)-3-cyclohexen-1-amine; BOC-(R)-3-Cyclohexenylamine; (1R,3R)-rel-3-Cyclohexene-1-carbamic acid 1,1-dimethylethyl ester; (R)-1-N-Boc-amino-3-cyclohexene
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[(1R)-Cyclohex-3-En-1-Yl]Carbamate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >98%), enantiomeric excess (typically >99% ee), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.