Description

(2-Carbamoyl-2-Hydroxy-Ethyl)-Carbamic Acid tert-Butyl Ester (Wx642127) is a protected amino acid derivative, specifically a tert-butyloxycarbonyl (Boc)-protected glycinamide analog, serving as a crucial building block in advanced organic synthesis. Its primary value lies in providing a reactive amine group that is shielded from undesired reactions during multi-step synthetic sequences, enabling the precise construction of complex molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing novel active pharmaceutical ingredients (APIs), peptides, and other fine chemicals where controlled functional group manipulation is paramount.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for amine functionalities in complex organic syntheses.
• Bioconjugation: Serves as a precursor for linkers and spacers used in antibody-drug conjugates (ADCs) and other bioconjugation technologies.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for biochemical research.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and herbicides.

Basic Information

Product Name	(2-Carbamoyl-2-Hydroxy-Ethyl)-Carbamic Acid tert-Butyl Ester (Wx642127)
CAS No.	1350475-32-9
Molecular Formula	C8H16N2O4
Molecular Weight	204.23 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-2-amino-2-hydroxyacetamide; 2-[(tert-Butoxycarbonyl)amino]-2-hydroxyacetamide; Boc-Aminooxyacetamide; Boc-NH-O-CH2-CONH2; (2-Amino-2-oxoethoxy)carbamic acid tert-butyl ester; tert-Butyl N-(2-amino-2-oxoethoxy)carbamate; Wx642127
EINECS	Contact for details

Quality Control

Our (2-Carbamoyl-2-Hydroxy-Ethyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.