Description

N,N',N''-[Nitrilotris(2,1-Ethanediylthio-2,1-Ethanediyl)]Tris[5-(Dimethylamino)-1-Naphthalenesulfonamide is a sophisticated, multi-functional chemical compound featuring a nitrilotris core linked to dansylamide fluorophore units via thioether spacers. This structure is engineered for high-affinity binding and sensitive detection, making it a critical reagent in advanced analytical and diagnostic applications. It is primarily utilized by research institutions and industrial laboratories specializing in fluorescence-based sensing, metal ion chelation studies, and the development of novel biochemical probes.

Application

• Fluorescent Chemosensor Development: Serves as a core building block for creating highly selective and sensitive fluorescent probes for the detection of transition metal ions, particularly soft metals like Hg²⁺, Cu²⁺, and Ag⁺.
• Bioconjugation and Labeling: Used to tag proteins, peptides, or other biomolecules due to the reactive sulfonamide groups and the strong fluorescence of the dansyl moiety, enabling tracking and imaging studies.
• Material Science Research: Incorporated into polymers or nanomaterials to impart metal-chelating properties and fluorescence for creating smart, responsive materials or sensors.
• Analytical Chemistry Standards: Employed as a reference standard or a complexing agent in chromatographic methods (HPLC) and spectroscopic analysis for method development and validation.
• Pharmaceutical Research: Investigated for potential use in drug delivery systems where targeted release is triggered by specific biological ions or conditions.
• Environmental Monitoring: Forms the basis for assay kits or sensor strips designed to detect heavy metal contamination in water and soil samples.

Basic Information

Product Name	N,N',N''-[Nitrilotris(2,1-Ethanediylthio-2,1-Ethanediyl)]Tris[5-(Dimethylamino)-1-Naphthalenesulfonamide
CAS No.	1350343-28-0
Molecular Formula	C₄₈H₆₀N₁₀O₆S₆
Molecular Weight	1061.44 g/mol
Synonyms	Tris(2-((5-(dimethylamino)naphthalene-1-sulfonamido)ethylthio)ethyl)amine; Nitrilotris(ethane-2,1-diylthioethane-2,1-diyl) tris(5-(dimethylamino)naphthalene-1-sulfonamide); Dansylamide-based Trithioether Ligand; Fluorescent Tridentate Thioether Ligand; NTA(Thioether-Dansyl)₃; Metal Ion Fluorescent Probe Precursor; 1,1',1''-Nitrilotris(2-((2-((5-(dimethylamino)-1-naphthalenesulfonyl)amino)ethyl)thio)ethane)
EINECS	Contact for details

Quality Control

Our production of N,N',N''-[Nitrilotris(2,1-Ethanediylthio-2,1-Ethanediyl)]Tris[5-(Dimethylamino)-1-Naphthalenesulfonamide adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, critical for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and Mass Spectrometry. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a desiccated environment to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Loss on Drying	≤ 2.0 %
Heavy Metals	≤ 20 ppm
Fluorescence Properties	Characteristic excitation/emission maxima

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.