Description

(R)-1-Cyclohexanecarbonylpyrrolidin-3-Amine Hydrochloride CAS NO 1349699-91-7 is a high-purity chiral amine derivative, specifically engineered as a critical building block in advanced pharmaceutical synthesis. Its value lies in providing a stereochemically defined scaffold essential for developing enantiomerically pure active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in areas requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) and metabolic disorder targets.
• Asymmetric Synthesis: Serves as a precursor or catalyst ligand in stereoselective chemical reactions to produce single-enantiomer compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to improve drug potency and selectivity.
• API Manufacturing: Incorporated into the synthetic pathway for the commercial production of specific, proprietary active pharmaceutical ingredients.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis services catering to the specific needs of pharmaceutical and biotech clients.

Basic Information

Product Name	(R)-1-Cyclohexanecarbonylpyrrolidin-3-Amine Hydrochloride
CAS No.	1349699-91-7
Molecular Formula	C11H21ClN2O
Molecular Weight	232.75 g/mol
Synonyms	(R)-3-Amino-1-(cyclohexylcarbonyl)pyrrolidine hydrochloride; (3R)-1-(Cyclohexylcarbonyl)-3-pyrrolidinamine hydrochloride; (R)-1-Cyclohexanoyl-3-aminopyrrolidine HCl; (R)-N-(3-Aminopyrrolidin-1-yl)cyclohexanecarboxamide hydrochloride; Pyrrolidin-3-amine, 1-(cyclohexylcarbonyl)-, (3R)-, hydrochloride; (R)-1-Cyclohexylcarbonyl-3-aminopyrrolidine hydrochloride; (R)-1-(Cyclohexanecarbonyl)pyrrolidin-3-amine HCl
EINECS	Contact for details

Quality Control

Our (R)-1-Cyclohexanecarbonylpyrrolidin-3-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, chiral HPLC) and spectroscopic confirmation are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.