Description

Chidamide-13C7 CAS NO 1348337-81-4 is a high-purity, stable isotope-labeled analog of the histone deacetylase (HDAC) inhibitor Chidamide. This compound is essential for precise and reliable quantitative analysis in pharmaceutical research and development, particularly in pharmacokinetic and metabolic studies. It is a critical tool for scientists and quality control laboratories in the pharmaceutical, biotechnology, and contract research organization (CRO) sectors who require definitive internal standards for mass spectrometry.

Application

• Internal Standard for LC-MS/MS: Primary application as a quantitative internal standard in bioanalytical method development and validation for Chidamide.
• Drug Metabolism and Pharmacokinetics (DMPK): Used in absorption, distribution, metabolism, and excretion (ADME) studies to track drug and metabolite levels.
• Clinical Trial Support: Enables accurate measurement of Chidamide concentrations in biological matrices (plasma, serum, urine) during clinical phases.
• Biomarker Research: Facilitates precise quantification in studies investigating HDAC inhibition and related epigenetic mechanisms.
• Quality Control & Reference Standard: Serves as a certified reference material for assay purity testing and method calibration in pharmaceutical QC labs.

Basic Information

Product Name	Chidamide-13C7
CAS No.	1348337-81-4
Molecular Formula	C2113C7H20N4O4
Molecular Weight	~411.4 g/mol
Synonyms	Epidaza-13C7; HBI-8000-13C7; CS055-13C7; Tucidinostat-13C7; Chidamide (phenyl-13C6, carbonyl-13C); N-(2-Amino-4-fluorophenyl)-4-[[[(113C6)cyclohexyl]carbonyl-13C]amino]methyl]benzamide; Isotopically Labeled Chidamide; 13C7-Labeled HDAC Inhibitor
EINECS	Contact for details

Quality Control

Our Chidamide-13C7 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for critical research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically ≥99% 13C7), chemical purity (by HPLC), and confirmatory structural data. We adhere to relevant industry standards for reference materials to ensure reliable and reproducible results in your analytical workflows.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥99 atom % 13C7
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.