Description

Escitalopram Desfluoro Analogue is a key pharmaceutical intermediate and reference standard used in research and development. This compound is of significant importance for the synthesis and analytical characterization of active pharmaceutical ingredients (APIs) within the selective serotonin reuptake inhibitor (SSRI) class. It is primarily required by pharmaceutical manufacturers, contract research organizations (CROs), and analytical laboratories for process development, quality control, and regulatory compliance activities.

Application

• Pharmaceutical Intermediate: A critical building block in the research-scale synthesis of novel escitalopram derivatives and related therapeutic compounds.
• Reference Standard: Used as a certified reference material (CRM) for method development, validation, and impurity profiling in HPLC and LC-MS analysis.
• Metabolite Studies: Serves as an analytical standard in pharmacokinetic and drug metabolism research to understand metabolic pathways.
• Process Chemistry R&D: Employed in route scouting and optimization studies for the manufacturing of SSRIs and other neuroactive agents.
• Quality Control & Assurance: Essential for identifying and quantifying related substances and degradation products in final API batches to ensure purity specifications are met.
• Academic Research: Used in university and institutional labs for studying structure-activity relationships (SAR) and neuropharmacology.

Basic Information

Product Name	Escitalopram Desfluoro Analogue
CAS No.	1346617-30-8
Molecular Formula	C20H21N2O
Molecular Weight	305.40 g/mol
Synonyms	Desfluoro Escitalopram; Escitalopram Desfluoro Impurity; 1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile Desfluoro Derivative; (S)-1-(4-Fluorophenyl)-1,3-dihydro-3-[(dimethylamino)methyl]-5-isobenzofurancarbonitrile Desfluoro Analogue; Citalopram Desfluoro Derivative; SCT Desfluoro Analogue; SSRRI Intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Escitalopram Desfluoro Analogue is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all test results against agreed specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.