Description

(4S)-4-Hydroxy-4-(1,1,2,2,2-Pentadeuterioethyl)-7,8-Dihydro-1H-Pyrano[3,4-F]Indolizine-3,6,10-Trione is a deuterated derivative of a complex heterocyclic compound, featuring a pentadeuterated ethyl group which is critical for advanced research applications. This compound is valued for its role as a stable isotope-labeled intermediate or reference standard in analytical chemistry and life sciences. It is primarily utilized by researchers and developers in the pharmaceutical, agrochemical, and academic sectors for metabolic studies, tracer analysis, and method development.

Application

• Pharmaceutical Research: Used as a stable isotope-labeled internal standard in LC-MS and GC-MS for the quantitative bioanalysis of drug candidates and metabolites.
• Metabolic Pathway Tracing: Serves as a deuterium-labeled tracer in studies investigating biochemical pathways and drug metabolism (ADME).
• Analytical Method Development: Employed as a high-purity reference material to validate and calibrate analytical methods for complex heterocyclic compounds.
• Chemical Synthesis Intermediate: Acts as a specialized building block for the synthesis of novel deuterated compounds in medicinal chemistry.
• Agrochemical Research: Potential use in the development and analysis of labeled agrochemicals and their environmental fate.
• Academic & Institutional Research: Applied in fundamental chemical research involving isotope effects, reaction mechanisms, and spectroscopy.

Basic Information

Item	Details
Product Name	(4S)-4-Hydroxy-4-(1,1,2,2,2-Pentadeuterioethyl)-7,8-Dihydro-1H-Pyrano[3,4-F]Indolizine-3,6,10-Trione
CAS No.	1346617-23-9
Molecular Formula	C13H8D5NO5
Molecular Weight	Contact for details
Synonyms	4-Hydroxy-4-(1,1,2,2,2-pentadeuterioethyl)-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10-trione; Deuterated Pyranoindolizinetrione Derivative; (4S)-4-Hydroxy-4-(pentadeuterioethyl)dihydropyranoindolizinetrione; CAS 1346617-23-9; 1H-Pyrano[3,4-f]indolizine-3,6,10-trione, 7,8-dihydro-4-hydroxy-4-(1,1,2,2,2-pentadeuterioethyl)-, (4S)-; Stable Isotope Labeled Heterocycle
EINECS	Contact for details

Quality Control

Every batch of (4S)-4-Hydroxy-4-(1,1,2,2,2-Pentadeuterioethyl)-7,8-Dihydro-1H-Pyrano[3,4-F]Indolizine-3,6,10-Trione is manufactured and analyzed under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity research chemicals. Certificates of Analysis (COA) detailing purity, isotopic enrichment, and identity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider conditions under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment	≥ 95 atom % D
Water Content	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.