Description

Decyclohexanol-Ethoxycarbonyl-o-Desmethyl Venlafaxine-D6 CAS NO 1346605-17-1 is a high-purity, deuterium-labeled analog of a key venlafaxine metabolite, designed for advanced analytical and research applications. This compound is critically important for ensuring accuracy and reliability in quantitative bioanalysis, pharmacokinetic studies, and drug metabolism research. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers engaged in method development and validation.

Application

• Use as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) for the precise quantification of venlafaxine and its metabolites in biological matrices.
• Critical component in pharmacokinetic (PK) and bioequivalence studies to track drug absorption, distribution, metabolism, and excretion.
• Essential for drug metabolism and disposition (DMPK) research, aiding in the identification and characterization of metabolic pathways.
• Facilitates clinical trial support by providing reliable data for therapeutic drug monitoring and patient compliance studies.
• Supports forensic and toxicological analysis for the accurate detection of venlafaxine in complex samples.
• Enables method development and validation in regulatory-compliant environments (e.g., FDA, EMA guidelines).
• Used in stable isotope dilution assays to correct for analyte loss during sample preparation and instrument variability.

Basic Information

Product Name	Decyclohexanol-Ethoxycarbonyl-o-Desmethyl Venlafaxine-D6
CAS No.	1346605-17-1
Molecular Formula	C19H25D6NO3
Molecular Weight	327.48 g/mol (approx.)
Synonyms	O-Desmethyl Venlafaxine D6 Ethoxycarbonyl Derivative; ODV D6 Ethoxycarbonyl Ester; N-Descyclohexyl Venlafaxine Metabolite-D6 Ester; Deuterated Venlafaxine Metabolite Standard; [D6]-Decyclohexanol-Ethoxycarbonyl-o-Desmethyl Venlafaxine; 1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol-1,1,2,2,6,6-D6 ethyl carbonate; Ethyl [2-(dimethylamino)-1-(4-methoxyphenyl)ethyl](hydroxy-D6)cyclohexylcarbamate
EINECS	Contact for details

Quality Control

This deuterated standard is manufactured under strict quality control protocols to ensure exceptional isotopic purity and chemical integrity, essential for trace-level analysis. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation via advanced spectroscopic methods. Our quality systems are designed to meet the rigorous demands of GLP/GMP-compliant research environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term stability, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.