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Des[[n-(1,1-Dimethylethyl)Amino]Carbonyl] 17-(Propionyl) Finasteride CAS NO 1346604-11-2


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CAS No.:1346604-11-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Des[[n-(1,1-Dimethylethyl)Amino]Carbonyl] 17-(Propionyl) Finasteride is a key pharmaceutical intermediate, specifically a modified finasteride derivative. This compound is of critical importance for the research and development of advanced therapeutic agents targeting androgen-related pathways. It is primarily needed by pharmaceutical R&D laboratories and manufacturers specializing in the synthesis of active pharmaceutical ingredients (APIs) for urological and dermatological treatments.

Application

  • Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel finasteride analogs and related 5α-reductase inhibitors.
  • Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies to develop new therapeutic entities.
  • Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the controlled production of specialized steroid-based APIs.
  • Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition mechanisms.
  • Process Development: Utilized in scaling up and optimizing synthetic routes for commercial manufacturing.

Basic Information

Product Name Des[[n-(1,1-Dimethylethyl)Amino]Carbonyl] 17-(Propionyl) Finasteride
CAS No. 1346604-11-2
Molecular Formula C26H41N3O3
Molecular Weight 443.63 g/mol
Synonyms 17-Propionyl Finasteride tert-Butylcarbamate Derivative; N-tert-Butoxycarbonyl-17-propionyl Finasteride; Finasteride 17-propionate tert-butylcarbamate; 17-O-Propionylfinasteride N-(tert-butoxycarbonyl); BOC-Finasteride 17-propionate; (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(tert-Butoxycarbonyl)-7-propionyloxy-1,2,3,4,4a,4b,5,6,6a,7,9a,9b,10,11-tetradecahydro-4a,6a-dimethyl-2-oxonaphtho[2,1-f]quinoline-4-carboxamide
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Quality Control

Our Des[[n-(1,1-Dimethylethyl)Amino]Carbonyl] 17-(Propionyl) Finasteride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Single Impurity (HPLC) ≤ 1.0%
Total Impurities (HPLC) ≤ 2.0%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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