Description

n-Trifluoroacetyl-1,3-Propylenediamine Hydrochloride is a high-purity, specialty organic salt featuring a reactive trifluoroacetyl-protected diamine moiety. This compound is a critical building block in advanced organic synthesis, valued for its role in introducing fluorinated and amine-functionalized components into target molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental stability.
• Peptide Mimetics & Linker Chemistry: Functions as a versatile building block for creating peptide analogs and bioconjugation linkers, leveraging the reactivity of the diamine group.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorinated Polymer Research: Acts as a monomer or modifier in the synthesis of specialty polymers with enhanced chemical resistance and unique surface properties.
• Diagnostic Reagent Manufacturing: Utilized in the production of contrast agents and fluorescent probes for medical imaging and bioassays.

Basic Information

Product Name	n-Trifluoroacetyl-1,3-Propylenediamine Hydrochloride
CAS No.	1346604-02-1
Molecular Formula	C5H9ClF3N2O
Molecular Weight	205.58 g/mol
Synonyms	1,3-Propanediamine, N1-(2,2,2-trifluoroacetyl)-, hydrochloride (1:1); 3-[(2,2,2-Trifluoroacetyl)amino]propylamine hydrochloride; N-(3-Aminopropyl)-2,2,2-trifluoroacetamide hydrochloride; Trifluoroacetyl-1,3-diaminopropane hydrochloride; TFAPDA·HCl; N1-Trifluoroacetylpropane-1,3-diamine hydrochloride
EINECS	Contact for details

Quality Control

Our n-Trifluoroacetyl-1,3-Propylenediamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure identity, purity, and conformity to stringent specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.