Description

Alimemazine D6 is a deuterated isotopologue of the phenothiazine derivative alimemazine, specifically designed for use as an internal standard in quantitative analytical methods. This high-purity reference material is essential for ensuring accuracy and reliability in mass spectrometry and other advanced analytical techniques, where precise measurement is critical. It is primarily utilized by pharmaceutical research and development laboratories, contract research organizations (CROs), and analytical service providers engaged in method development, pharmacokinetic studies, and quality control for drug substances and metabolites.

Application

• Internal Standard for LC-MS/MS: Serves as a critical, non-interfering reference compound for the precise quantification of alimemazine and its metabolites in complex biological matrices like plasma, serum, and urine.
• Pharmaceutical R&D: Used in method development and validation studies to support drug discovery, pharmacokinetic (PK), and pharmacodynamic (PD) research programs.
• Bioanalytical Testing: Enables accurate and reproducible results in bioequivalence studies and clinical trial sample analysis within GLP/GMP-compliant laboratories.
• Metabolite Identification & Profiling: Aids in the identification and structural elucidation of drug metabolites through comparative mass spectrometric analysis.
• Forensic & Toxicology Analysis: Supports the accurate detection and quantification of alimemazine in forensic investigations and toxicological screenings.
• Stability-Indicating Assay Development: Employed in developing robust analytical methods to monitor the stability and degradation products of pharmaceutical formulations.

Basic Information

Product Name	Alimemazine D6
CAS No.	1346603-88-0
Molecular Formula	C18H16D6N2S
Molecular Weight	Approx. 300.48 g/mol
Synonyms	Trimeprazine D6; Deuterated Alimemazine; Alimemazine-(ethyl-d6); 10-[3-(Dimethylamino)-2-methylpropyl]phenothiazine-d6; 10H-Phenothiazine-10-propanamine, N,N,β-trimethyl-, deuterated; Trimeprazine-d6; Internal Standard for Alimemazine
EINECS	Contact for details

Quality Control

Every batch of Alimemazine D6 is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to support its use in regulated environments. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as isotopic purity, chemical purity, and absence of interfering impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D6)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.