Description

Deferiprone-D3 is a deuterium-labeled analog of the iron-chelating agent Deferiprone, specifically designed for use as an internal standard in quantitative bioanalytical studies. This high-purity stable isotope-labeled compound is essential for ensuring the accuracy and reliability of pharmacokinetic and metabolic research, providing superior precision over non-labeled standards. It is a critical tool for pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions conducting advanced mass spectrometry (MS) and liquid chromatography-mass spectrometry (LC-MS/MS) analysis.

Application

• Internal Standard for LC-MS/MS: Primary application as a stable isotope-labeled internal standard for the precise quantification of Deferiprone in complex biological matrices (e.g., plasma, serum, urine).
• Pharmacokinetic (PK) and Toxicokinetic (TK) Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Metabolite Identification and Profiling: Assists in the identification and quantification of drug metabolites using high-resolution mass spectrometry.
• Method Development and Validation: Critical for developing and validating robust, GLP-compliant bioanalytical methods with high specificity and minimal matrix effects.
• Drug-Drug Interaction Studies: Used in assays to study the potential impact of other compounds on the metabolism of Deferiprone.
• Quality Control in Pharmaceutical Analysis: Supports quality assurance processes in drug manufacturing and batch release testing.

Basic Information

Product Name	Deferiprone-D3
CAS No.	1346601-82-8
Molecular Formula	C7H6D3NO2
Molecular Weight	142.17 g/mol
Synonyms	3-Hydroxy-1,2-dimethyl-4(1H)-pyridone-d3; 1,2-Dimethyl-3-hydroxy-4-pyridone-d3; L1-d3; CP20-d3; Deferiprone (trideuterated); Deferiprone-d3 (Internal Standard); 1,2-Dimethyl-3-hydroxypyrid-4-one-d3
EINECS	Contact for details

Quality Control

Our Deferiprone-D3 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity required for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D, atom %), chemical purity (by HPLC), and confirmation of structure. We adhere to relevant industry standards for stable isotope-labeled compounds to guarantee consistency and reliability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D, atom %)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.