Description

2-[[(4-Cyanophenyl)Amino]Methyl]-1-Methyl-1H-Benzimidazole-5-Carboxylic-D3 Acid Ethyl Ester is a deuterated benzimidazole derivative, a high-value synthetic intermediate designed for advanced research and development. This compound is critical for applications requiring isotopic labeling, such as in the creation of internal standards for mass spectrometry and in metabolic studies. It is primarily sought after by pharmaceutical R&D teams, analytical laboratories, and specialty chemical manufacturers working on novel drug candidates and diagnostic tools.

Application

• Pharmaceutical Research & Development: Serves as a key deuterated building block in the synthesis of novel drug candidates, particularly for pharmacokinetic and metabolic stability studies.
• Analytical Chemistry & Mass Spectrometry: Used as a stable isotope-labeled internal standard for the accurate quantification of parent compounds in complex biological matrices via LC-MS/MS.
• Metabolite Identification & Tracing: Enables precise tracking of drug metabolism pathways in preclinical and clinical research due to its deuterium labeling.
• Proteomics & Biomarker Discovery: Employed in the development of chemical probes and reagents for targeted protein analysis and biomarker validation.
• Specialty Chemical Synthesis: Acts as a precursor for synthesizing more complex deuterated molecules for various high-tech applications.

Basic Information

Product Name	2-[[(4-Cyanophenyl)Amino]Methyl]-1-Methyl-1H-Benzimidazole-5-Carboxylic-D3 Acid Ethyl Ester
CAS No.	1346601-47-5
Molecular Formula	C19H16D3N4O2
Molecular Weight	336.40 g/mol (approx.)
Synonyms	Ethyl 2-[[(4-cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazole-5-carboxylate-d3; 1-Methyl-2-[(4-cyanophenylamino)methyl]-1H-benzimidazole-5-carboxylic Acid Ethyl Ester-d3; Benzimidazole-5-carboxylic Acid Ethyl Ester-d3 Derivative; Deuterated Benzimidazole Ester; CAS 1346601-47-5; 2-[(4-Cyanophenylaminomethyl)]-1-methyl-1H-benzimidazole-5-carboxylic Acid Ethyl-d3 Ester
EINECS	Contact for details

Quality Control

Our deuterated chemical intermediates are produced under strict quality protocols to ensure batch-to-batch consistency and high isotopic purity. Each lot is characterized using advanced analytical techniques including NMR (¹H, ¹³C), HPLC, and mass spectrometry to confirm chemical and isotopic identity, purity, and absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.