Description

3',4'-Dimethoxy-2-Fluoro-4-Methylbiphenyl is a high-purity fluorinated biphenyl derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular architecture, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working on new active ingredients, particularly in the life sciences sector.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing complex aryl-ether motifs.
• Agrochemical Research: Used in developing new-generation herbicides, fungicides, and plant growth regulators where the fluorinated biphenyl core enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a sophisticated intermediate for creating fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a ligand precursor in catalytic systems due to its electron-donating methoxy groups and steric profile.
• Material Science Research: Acts as a monomer or modifying agent in the development of specialized polymers and advanced organic materials with tailored thermal and optical properties.

Basic Information

Product Name	3',4'-Dimethoxy-2-Fluoro-4-Methylbiphenyl
CAS No.	1346601-39-5
Molecular Formula	C₁₅H₁₅FO₂
Molecular Weight	246.28 g/mol
Synonyms	2-Fluoro-4'-methyl-3,4-dimethoxybiphenyl; 4'-Methyl-3,4-dimethoxy-2-fluorobiphenyl; 1-Fluoro-2-(4-methyl-3,4-dimethoxyphenyl)benzene; 2-Fluoro-3',4'-dimethoxy-4-methyl-1,1'-biphenyl; [1,1'-Biphenyl]-2-fluoro-4'-methyl-3,4-dimethoxy-; 3,4-Dimethoxy-2-fluoro-4'-methylbiphenyl
EINECS	Contact for details

Quality Control

Every batch of 3',4'-Dimethoxy-2-Fluoro-4-Methylbiphenyl is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, and NMR is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.