Description

Blonanserin-D5 is a deuterated analog of the atypical antipsychotic Blonanserin, specifically designed for use as an internal standard in analytical chemistry. This high-purity reference material is essential for ensuring the accuracy and reliability of quantitative analyses in pharmaceutical research and development. It is primarily used by analytical chemists and quality control laboratories in the pharmaceutical industry for method development, validation, and bioanalytical studies.

Application

• Internal Standard for LC-MS/MS: Serves as a critical deuterated internal standard for the precise quantification of Blonanserin in complex biological matrices such as plasma, serum, and tissue homogenates.
• Pharmacokinetic and Bioavailability Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) in clinical and pre-clinical research.
• Method Development and Validation: Used as a reference compound to develop, optimize, and validate robust high-performance liquid chromatography (HPLC) and mass spectrometry (MS) analytical methods.
• Quality Control and Assurance: Supports impurity profiling and assay verification in the manufacturing process of Blonanserin active pharmaceutical ingredients (APIs) and finished dosage forms.
• Forensic and Clinical Toxicology: Aids in the accurate detection and quantification of Blonanserin in forensic analysis and therapeutic drug monitoring.
• Metabolite Identification: Assists in the identification and study of Blonanserin metabolites in in vitro and in vivo systems.

Basic Information

Product Name	Blonanserin-D5
CAS No.	1346599-86-7
Molecular Formula	C23H25D5FN2O
Molecular Weight	368.52 g/mol
Synonyms	2-(4-Ethyl-1-piperazinyl)-4-(4-fluorophenyl)-5,6,7,8,9-pentadeutero-5,6,7,8,9-tetrahydrocycloocta[b]pyridine-3-carbonitrile; Blonanserin-d5; AD-5423-d5; Lonasen-d5; Deuterated Blonanserin; Blonanserin (phenyl-d5)
EINECS	Contact for details

Quality Control

Our Blonanserin-D5 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and isotopic enrichment suitable for sensitive analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and all analytical results is provided with every shipment to guarantee traceability and compliance with your research standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥98.0%
Isotopic Purity (D-enrichment)	≥98 atom % D
Chemical Purity (by NMR)	≥95.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.