Description

Rac N,n-Didesmethyl-n-(4-Hydroxyphenethyl)-o-Desmethyl Venlafaxine-D11 is a deuterated analog of a key venlafaxine metabolite, specifically designed for use as a high-purity internal standard in analytical chemistry. This compound is critical for ensuring the accuracy and reliability of quantitative analyses, particularly in pharmacokinetic and bioequivalence studies. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and forensic toxicology units that require definitive analytical methods.

Application

• Internal Standard for LC-MS/MS: Essential for the precise quantification of venlafaxine and its metabolites in biological matrices (e.g., plasma, serum, urine) using mass spectrometry.
• Pharmaceutical R&D: Supports method development and validation for drug metabolism and pharmacokinetics (DMPK) studies of antidepressants.
• Forensic Toxicology: Enables accurate measurement of drug concentrations in forensic investigations and workplace drug testing.
• Clinical Research: Used in bioanalytical assays for clinical trials to monitor drug levels and metabolite profiles in patients.
• Reference Material: Serves as a certified reference standard for calibrating analytical instruments and ensuring regulatory compliance.
• Metabolite Pathway Studies: Aids in the elucidation of metabolic pathways and the identification of minor metabolites.

Basic Information

Product Name	Rac N,n-Didesmethyl-n-(4-Hydroxyphenethyl)-o-Desmethyl Venlafaxine-D11
CAS No.	1346598-87-5
Molecular Formula	C17H16D11NO2
Molecular Weight	Contact for details
Synonyms	O-Desmethylvenlafaxine-d11 (N,N-Didesmethyl Metabolite); N-Desmethyl-O-desmethylvenlafaxine-d11; N,N-Didesmethyl ODV-d11; Venlafaxine Metabolite-d11; 1-[2-(Dimethylamino)-1-(4-hydroxyphenyl)ethyl]cyclohexanol-d11; 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol-d11; (R,S)-N,N-Didesmethyl-O-desmethylvenlafaxine-d11
EINECS	Contact for details

Quality Control

Every batch of our deuterated standards is produced under strict quality management systems to guarantee exceptional isotopic purity and chemical stability. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards for reference materials. Certificates of Analysis (COA) detailing batch-specific purity, isotopic enrichment, and analytical results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the product to equilibrate to room temperature in a dry environment before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.