Description

α-[(Diethyl-D10)Amino]Benzeneacetic Acid Ethyl Ester is a high-purity, deuterated organic compound of significant value in advanced research and development. This deuterium-labeled analog is specifically designed for use as a critical internal standard or tracer in quantitative mass spectrometry and metabolic studies, ensuring superior accuracy and reliability. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers engaged in pharmacokinetics, drug metabolism, and proteomics research where precise isotopic labeling is required.

Application

• Internal Standard for LC-MS/MS: Serves as a stable, non-interfering reference compound for the precise quantification of its non-deuterated counterpart in complex biological matrices like plasma, serum, and tissue homogenates.
• Metabolic Pathway Tracing: Used as a deuterium-labeled tracer in drug metabolism and pharmacokinetics (DMPK) studies to elucidate metabolic pathways and identify metabolites.
• Proteomics and Biomarker Research: Employed in stable isotope labeling techniques for the relative and absolute quantification of proteins and small molecule biomarkers.
• Pharmaceutical Reference Standard: Acts as a certified reference material (CRM) for method development, validation, and quality control in analytical laboratories.
• Isotope Dilution Mass Spectrometry (IDMS): A key component in high-accuracy IDMS methods, crucial for clinical diagnostics and regulatory bioanalysis.
• Chemical Synthesis Intermediate: Functions as a specialized building block for the synthesis of more complex deuterated molecules for research purposes.

Basic Information

Item	Detail
Product Name	α-[(Diethyl-D10)Amino]Benzeneacetic Acid Ethyl Ester
CAS No.	1346597-98-5
Molecular Formula	C14D10H11NO2
Molecular Weight	233.31 g/mol (deuterated form)
Synonyms	Ethyl 2-((Diethyl-d10)amino)-2-phenylacetate; Ethyl (Diethyl-d10)aminophenylacetate; 2-((Diethyl-d10)amino)-2-phenylacetic acid ethyl ester; Deutrated Tropate Ethyl Ester; α-(Diethyl-d10-amino)benzeneacetic acid ethyl ester; (Diethyl-d10)amino(phenyl)acetic acid ethyl ester; Ethyl α-[(diethyl-d10)amino]benzeneacetate
EINECS	Contact for details

Quality Control

Every batch of our α-[(Diethyl-D10)Amino]Benzeneacetic Acid Ethyl Ester is manufactured and analyzed under strict quality management systems. We guarantee high chemical purity and isotopic enrichment, with comprehensive testing including assay by NMR or HPLC, deuterium incorporation by MS, and identification by IR and NMR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. Keep the container tightly sealed under an inert atmosphere if necessary for long-term storage to maintain stability and isotopic purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Incorporation by MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.