Description

Rac-Clopidogrel-Mp Endo Derivative-13C,D3 is a stable isotope-labeled analog of a key clopidogrel intermediate, specifically designed for use as an internal standard in quantitative bioanalytical methods. This compound is essential for ensuring the accuracy and reliability of pharmacokinetic and metabolic studies, providing critical data for drug development and regulatory submissions. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of analytical reference standards who demand high chemical purity and isotopic enrichment for precise mass spectrometry applications.

Application

• Internal Standard for LC-MS/MS: Serves as a critical internal standard in the quantitative bioanalysis of clopidogrel and its metabolites in biological matrices (plasma, serum, urine).
• Drug Metabolism and Pharmacokinetics (DMPK): Used in absorption, distribution, metabolism, and excretion (ADME) studies to track and quantify the parent drug and metabolites.
• Clinical Research: Enables precise therapeutic drug monitoring (TDM) and pharmacogenetic studies related to clopidogrel response variability.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities and degradants during API manufacturing.
• Reference Material Production: Used by certified reference material (CRM) suppliers to create calibrated standards for laboratory use.
• Forensic and Anti-Doping Analysis: Supports specialized testing protocols requiring high specificity and sensitivity for clopidogrel detection.

Basic Information

Product Name	Rac-Clopidogrel-Mp Endo Derivative-13C,D3
CAS No.	1346597-76-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Clopidogrel-d3-13C (Methyl-13C, d3) Intermediate; Methyl α-5-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)(2-chlorophenyl)acetate-13C,d3; (RS)-Clopidogrel-13C,d3; (Rac)-Clopidogrel Methyl Ester-13C,d3; Clopidogrel Related Compound-13C,d3; Clopidogrel Carboxylic Acid Methyl Ester-13C,d3; 2-(2-Chlorophenyl)-2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)acetic acid methyl ester-13C,d3
EINECS	Contact for details

Quality Control

Every batch of Rac-Clopidogrel-Mp Endo Derivative-13C,D3 is manufactured and analyzed under strict quality systems. We ensure compliance with the high-purity standards required for analytical and research applications, with a focus on isotopic purity, chemical purity, and stability. Certificates of Analysis (COA) are provided, detailing key parameters such as assay (HPLC), isotopic enrichment (MS), and related substances. Our quality commitment supports traceability and data integrity for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or CoA. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (MS)	≥99.0 atom % 13C; ≥98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.