Description

5-Iodo-2-Methylnicotinonitrile CAS NO 1346533-56-9 is a versatile halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an iodine substituent and a nitrile group, makes it a valuable intermediate for constructing complex molecules through cross-coupling and functional group transformations. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or functionalizing agent for creating specialized polymers and liquid crystals.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions to form biaryl structures.
• Ligand and Catalyst Development: Utilized in the preparation of novel nitrogen-containing ligands for metal complexes.
• Chemical Biology Probes: Acts as a starting point for synthesizing molecular probes and tags for biological imaging and target identification.

Basic Information

Product Name	5-Iodo-2-Methylnicotinonitrile
CAS No.	1346533-56-9
Molecular Formula	C7H5IN2
Molecular Weight	244.03 g/mol
Synonyms	2-Methyl-5-iodonicotinonitrile; 5-Iodo-2-methyl-3-cyanopyridine; 3-Cyano-5-iodo-2-methylpyridine; 2-Methyl-5-iodopyridine-3-carbonitrile; 5-Iodo-2-picolinonitrile; Nicotinonitrile, 5-iodo-2-methyl-; Pyridine, 3-cyano-5-iodo-2-methyl-
EINECS	Contact for details

Quality Control

Our 5-Iodo-2-Methylnicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the high standards required for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.