Description

n-(6-Chloro-5-Iodopyridin-2-Yl)Pivalamide is a high-purity halogenated pyridine derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its unique molecular scaffold, which is essential for constructing complex active pharmaceutical ingredients (APIs) in medicinal chemistry. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in oncology and antiviral drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, especially kinase inhibitors.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogenated pyridine core.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization via cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the reactive iodine and chlorine substituents.
• Material Science: Potential monomer or additive in the research of specialty polymers and advanced organic materials.
• Contract Research & Development (CRO/CMO): Supplied to organizations conducting custom synthesis and process development for clients.

Basic Information

Product Name	n-(6-Chloro-5-Iodopyridin-2-Yl)Pivalamide
CAS No.	1346447-30-0
Molecular Formula	C11H12ClIN2O
Molecular Weight	350.59 g/mol
Synonyms	2-Pivalamido-6-chloro-5-iodopyridine; 6-Chloro-5-iodo-2-pivalamidopyridine; Pivalic acid (6-chloro-5-iodopyridin-2-yl)amide; N-(6-Chloro-5-iodo-2-pyridinyl)-2,2-dimethylpropanamide; 2,2-Dimethyl-N-(6-chloro-5-iodopyridin-2-yl)propanamide; 6-Chloro-5-iodopyridin-2-amine, N-pivaloyl derivative; 1346447-30-0
EINECS	Contact for details

Quality Control

Our n-(6-Chloro-5-Iodopyridin-2-Yl)Pivalamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to GMP-grade standards ensures the material is suitable for demanding research and pre-clinical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.