Description

3-(1,5-Naphthyridin-3-Yl)Prop-2-Yn-1-Ol is a high-purity organic building block featuring a naphthyridine core linked to a propargyl alcohol moiety. This compound is valued for its role as a key synthetic intermediate in the development of advanced pharmaceutical and agrochemical agents. It is primarily utilized by research and development chemists in the pharmaceutical, biotechnology, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection and pest management solutions.
• Material Science: Serves as a precursor for functionalized organic materials and ligands for catalytic systems.
• Chemical Biology: Employed in the synthesis of probes and tool compounds for studying biological processes and target engagement.
• Academic & Contract Research: Essential for medicinal chemistry programs and exploratory synthetic research in university and CRO laboratories.

Basic Information

Product Name	3-(1,5-Naphthyridin-3-Yl)Prop-2-Yn-1-Ol
CAS No.	1346446-91-0
Molecular Formula	C11H8N2O
Molecular Weight	184.20 g/mol
Synonyms	3-(1,5-Naphthyridin-3-yl)prop-2-yn-1-ol; 3-(1,5-Naphthyridin-3-yl)-2-propyn-1-ol; 1,5-Naphthyridine-3-propargyl alcohol; 3-(1,5-Naphthyridin-3-yl)propargyl alcohol; 3-(1,5-Naphthyridin-3-yl)propiolic alcohol; 3-(1,5-Naphthyridin-3-yl)prop-2-ynol; 3-(1,5-Naphthyridin-3-yl)-2-propynol
EINECS	Contact for details

Quality Control

Our 3-(1,5-Naphthyridin-3-Yl)Prop-2-Yn-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.