Description

3-Bromo-4-Fluoro-5-Nitrobenzamide is a high-purity, multi-functional aromatic building block of significant interest in advanced organic synthesis. Its unique halogenated and nitro-substituted benzamide structure makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogen and nitro functional groups for bioactivity.
• Material Science: Serves as a building block for advanced polymers, liquid crystals, and organic electronic materials due to its rigid aromatic core.
• Dye and Pigment Synthesis: An intermediate in the production of specialized dyes and pigments where the nitro and halogen groups influence color and stability.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Chemical Biology Probes: Used in the design and synthesis of molecular probes for studying biological processes and protein interactions.

Basic Information

Product Name	3-Bromo-4-Fluoro-5-Nitrobenzamide
CAS No.	1345471-86-4
Molecular Formula	C7H4BrFN2O3
Molecular Weight	263.02 g/mol
Synonyms	5-Nitro-3-bromo-4-fluorobenzamide; Benzamide, 3-bromo-4-fluoro-5-nitro-; 3-Bromo-4-fluoro-5-nitro-benzamide; 4-Fluoro-3-bromo-5-nitrobenzamide; 1345471-86-4; 3-Br-4-F-5-NO2-Benzamide
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Fluoro-5-Nitrobenzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere when appropriate for prolonged use. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.