Description

Ethyl 3-(2,2,2-Trifluoroethyl)-1,2,4-oxadiazole-5-carboxylate is a specialized fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the 1,2,4-oxadiazole ring and the trifluoroethyl moiety, which can impart desirable properties like metabolic stability and altered lipophilicity to target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and infectious diseases.
• Agrochemical Research: Serves as a versatile building block for synthesizing novel herbicides, fungicides, and insecticides with potentially enhanced efficacy and environmental profiles.
• Material Science Precursor: Used in the synthesis of advanced polymers and liquid crystals where the introduction of fluorine atoms can modify thermal stability and optical properties.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes and tags for studying biological systems and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Ethyl 3-(2,2,2-Trifluoroethyl)-1,2,4-oxadiazole-5-carboxylate
CAS No.	1343920-05-7
Molecular Formula	C7H7F3N2O3
Molecular Weight	224.14 g/mol
Synonyms	5-Carbethoxy-3-(2,2,2-trifluoroethyl)-1,2,4-oxadiazole; Ethyl 3-(trifluoroethyl)-1,2,4-oxadiazole-5-carboxylate; 1,2,4-Oxadiazole-5-carboxylic acid, 3-(2,2,2-trifluoroethyl)-, ethyl ester; 3-(2,2,2-Trifluoroethyl)-1,2,4-oxadiazole-5-carboxylic acid ethyl ester; 1343920-05-7; 5-Ethoxycarbonyl-3-(2,2,2-trifluoroethyl)-1,2,4-oxadiazole
EINECS	Contact for details

Quality Control

Our Ethyl 3-(2,2,2-Trifluoroethyl)-1,2,4-oxadiazole-5-carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ISO 9001 quality management standards, and our processes are designed to meet the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.