Description

2,6-Difluorophenyl Cyclopropyl Ketone is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its core value lies in its unique molecular architecture, which serves as a critical precursor for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate difluorophenyl and cyclopropyl motifs into complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluorophenyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic materials with tailored electronic or surface properties.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2,6-Difluorophenyl Cyclopropyl Ketone
CAS No.	1343158-95-1
Molecular Formula	C10H8F2O
Molecular Weight	182.17 g/mol
Synonyms	Cyclopropyl 2,6-Difluorophenyl Ketone; 1-Cyclopropyl-2,6-difluorophenylmethanone; 2,6-Difluorobenzoylcyclopropane; (2,6-Difluorophenyl)(cyclopropyl)methanone; 2,6-Difluoro-α-cyclopropylbenzyl Alcohol Ketone Form; Ketone, 2,6-difluorophenyl cyclopropyl
EINECS	Contact for details

Quality Control

Our 2,6-Difluorophenyl Cyclopropyl Ketone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.