Description

n-(4-Bromobenzyl)Oxetan-3-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique oxetane ring structure. This compound is valued for its role as a versatile building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with improved metabolic stability and pharmacokinetic properties. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of small-molecule therapeutics, particularly for oncology and central nervous system (CNS) targets.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization programs to introduce the oxetane moiety, which can enhance metabolic stability, solubility, and potency.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker component in the design of bifunctional molecules for targeted protein degradation.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying biological pathways and target validation.
• Agrochemical Research: Investigated as an intermediate for developing new crop protection agents with novel modes of action.
• Material Science: Potential precursor for specialty polymers and advanced functional materials.

Basic Information

Product Name	n-(4-Bromobenzyl)Oxetan-3-Amine
CAS No.	1342610-11-0
Molecular Formula	C10H12BrNO
Molecular Weight	242.11 g/mol
Synonyms	3-[(4-Bromophenyl)methyl]aminooxetane; 1-(4-Bromobenzyl)oxetan-3-amine; Oxetan-3-amine, N-[(4-bromophenyl)methyl]-; 4-Bromobenzyloxetan-3-amine; (4-Bromobenzyl)(oxetan-3-yl)amine; 3-Aminooxetane, N-(4-bromobenzyl)-; 1342610-11-0; N-(4-Bromobenzyl)-3-oxetanamine
EINECS	Contact for details

Quality Control

Every batch of n-(4-Bromobenzyl)Oxetan-3-Amine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency, meeting the stringent requirements of pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.