Description

tert-Butyl n-(1-Aminopropan-2-Yl)-n-Methylcarbamate CAS NO 1341670-13-0 is a specialized carbamate-protected amine derivative, serving as a crucial building block in advanced organic synthesis. Its primary value lies in providing a protected amine functionality, which is essential for the controlled, multi-step construction of complex molecules, particularly in pharmaceutical research. This intermediate is vital for medicinal chemists and process development scientists working on the synthesis of new active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals where selective amine manipulation is required.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Peptidomimetic Synthesis: Used to introduce modified amino acid residues into peptide chains to enhance stability, bioavailability, or biological activity.
• Protecting Group Strategy: The tert-butyloxycarbonyl (Boc) group protects the secondary amine during synthetic sequences, allowing for orthogonal deprotection.
• Agrochemical Research: Employed in the development of new pesticides and herbicides that require complex amine-containing structures.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis.
• Chemical Biology Probes: Useful for creating labeled or tagged molecules for studying biological pathways and protein interactions.

Basic Information

Item	Details
Product Name	tert-Butyl n-(1-Aminopropan-2-Yl)-n-Methylcarbamate
CAS No.	1341670-13-0
Molecular Formula	C10H22N2O2
Molecular Weight	202.30 g/mol
Synonyms	1,1-Dimethylethyl N-(1-Amino-2-propanyl)-N-methylcarbamate; tert-Butyl N-(1-amino-2-propyl)-N-methylcarbamate; N-Boc-N-methyl-1,2-diaminopropane; 2-[(tert-Butoxycarbonyl)(methyl)amino]propylamine; Boc-N-methyl-1,2-diaminopropane; N-Methyl-N-(1-amino-2-propyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl n-(1-Aminopropan-2-Yl)-n-Methylcarbamate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can compromise product integrity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.