Description

5,5,5-Trifluoropentan-2-One is a versatile fluorinated ketone building block of significant interest in advanced organic synthesis. Its value lies in the unique reactivity and physicochemical properties imparted by the terminal trifluoromethyl group, enabling the creation of novel compounds with enhanced stability and bioactivity. This intermediate is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the incorporation of the CF3 group into drug candidates, potentially improving metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, insecticides, and fungicides where fluorine substitution is critical for efficacy.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting technologies, influencing dielectric anisotropy and stability.
• Polymer & Coatings Modifier: Incorporated to create specialty polymers with altered surface properties, chemical resistance, and durability.
• Advanced Organic Synthesis: Employed in multi-step synthesis, including nucleophilic additions, reductions, and cyclization reactions to construct complex fluorinated architectures.
• Chemical Research & Development: A valuable tool for medicinal and process chemistry in both academic and industrial R&D laboratories exploring fluorine chemistry.

Basic Information

Product Name	5,5,5-Trifluoropentan-2-One
CAS No.	1341078-97-4
Molecular Formula	C5H7F3O
Molecular Weight	140.10 g/mol
Synonyms	1,1,1-Trifluoro-4-pentanone; 5,5,5-Trifluoro-2-pentanone; 4-Pentanone, 1,1,1-trifluoro-; 5,5,5-Trifluoropentan-2-one; 1,1,1-Trifluoropentan-4-one; Trifluoroethylacetone; 2-Oxo-5,5,5-trifluoropentane
EINECS	Contact for details

Quality Control

Our 5,5,5-Trifluoropentan-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.