Description

7-Bromo-5,8-Difluoro-3,4-Dihydronaphthalen-1(2H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated and fluorinated naphthalene core structure. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule therapeutics and agrochemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry research.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides and pesticides with enhanced efficacy.
• Organic Light-Emitting Diode (OLED) Materials: Used in the research and development of electron-transport or host materials due to its fluorinated aromatic structure.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in catalytic processes.
• Academic & Industrial R&D: Employed in chemical research to study structure-activity relationships and novel organic reactions.
• Fluorinated Compound Libraries: A valuable component for creating screening libraries in drug discovery programs.

Basic Information

Product Name	7-Bromo-5,8-Difluoro-3,4-Dihydronaphthalen-1(2H)-One
CAS No.	1341073-10-6
Molecular Formula	C10H5BrF2O
Molecular Weight	259.05 g/mol
Synonyms	7-Bromo-5,8-difluoro-3,4-dihydro-1(2H)-naphthalenone; 7-Bromo-5,8-difluoro-1-tetralone; 1(2H)-Naphthalenone, 7-bromo-5,8-difluoro-3,4-dihydro-; 7-Bromo-5,8-difluoro-3,4-dihydro-2H-naphthalen-1-one; 7-Bromo-5,8-difluoro-1-oxo-1,2,3,4-tetrahydronaphthalene
EINECS	Contact for details

Quality Control

Our 7-Bromo-5,8-Difluoro-3,4-Dihydronaphthalen-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.