Description

1-(Cyclopropylmethyl)-1,6-Dihydro-7H-Pyrrolo[2,3-C]Pyridin-7-One is a high-purity, advanced pharmaceutical intermediate with a complex fused heterocyclic structure. This compound is of significant commercial value as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for central nervous system (CNS) and oncological targets.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, especially those targeting kinase inhibition.
• Drug Discovery & Medicinal Chemistry: Serves as a versatile core scaffold for constructing compound libraries in high-throughput screening (HTS) campaigns.
• Process Research & Development (R&D): Used in route scouting and optimization studies to develop scalable and cost-effective manufacturing processes for new chemical entities (NCEs).
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) and novel heterocyclic chemistry.
• Reference Standard: Provides a high-purity analytical standard for quality control and method validation in API production.

Basic Information

Product Name	1-(Cyclopropylmethyl)-1,6-Dihydro-7H-Pyrrolo[2,3-C]Pyridin-7-One
CAS No.	1340802-62-1
Molecular Formula	C12H12N2O
Molecular Weight	200.24 g/mol
Synonyms	1-(Cyclopropylmethyl)-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-7-one; 7H-Pyrrolo[2,3-c]pyridin-7-one, 1,6-dihydro-1-(cyclopropylmethyl)-; 1-(Cyclopropylmethyl)-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one; 1-Cyclopropylmethyl-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one; 1-(Cyclopropylmethyl)-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one (CAS 1340802-62-1); Cyclopropylmethyl pyrrolopyridinone derivative
EINECS	Contact for details

Quality Control

Our production of 1-(Cyclopropylmethyl)-1,6-Dihydro-7H-Pyrrolo[2,3-C]Pyridin-7-One adheres to stringent internal quality standards designed to meet the exacting requirements of pharmaceutical R&D and manufacturing. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to include additional client-specific parameters upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.