Description

n-[2-(Trifluoromethyl)Benzyl]Oxetan-3-Amine CAS NO 1339894-12-0 is a high-value, fluorinated oxetane amine building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an oxetane ring and a benzyl group substituted with a trifluoromethyl moiety, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and resins with unique chemical resistance or optical properties.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create novel chiral ligands or catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Fluorine Chemistry: A valuable synthon for introducing fluorine atoms into complex molecular architectures to modulate lipophilicity, metabolic stability, and binding affinity.

Basic Information

Product Name	n-[2-(Trifluoromethyl)Benzyl]Oxetan-3-Amine
CAS No.	1339894-12-0
Molecular Formula	C11H12F3NO
Molecular Weight	231.21 g/mol
Synonyms	1-[[2-(Trifluoromethyl)phenyl]methyl]-3-oxetanamine; 3-Amino-1-[(2-trifluoromethyl)benzyl]oxetane; Oxetan-3-amine, N-[2-(trifluoromethyl)benzyl]-; 1-((2-(Trifluoromethyl)benzyl)amino)oxetan-3-ol (tautomer); 2-(Trifluoromethyl)benzyl oxetan-3-amine; 3-[[[2-(Trifluoromethyl)phenyl]methyl]amino]oxetane; (Oxetan-3-yl)-[2-(trifluoromethyl)benzyl]amine
EINECS	Contact for details

Quality Control

Our n-[2-(Trifluoromethyl)Benzyl]Oxetan-3-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical parameters such as assay, impurity profile, and residual solvents. Our quality commitment supports applications in cGMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.