Description

Propargyl-Peg1-Ch2Cootbu is a specialized bifunctional linker molecule featuring a propargyl group and a tert-butyl ester, connected by a short polyethylene glycol (PEG) spacer. This compound is engineered to facilitate controlled bioconjugation and chemical synthesis, offering a versatile handle for click chemistry and peptide coupling reactions. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, biotech, and advanced materials sectors who require precise and reliable building blocks for drug discovery, polymer science, and proteomics.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and antibody-drug conjugates (ADCs).
• Click Chemistry Reagent: Utilized in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for labeling, bioconjugation, and material surface functionalization.
• Peptide Synthesis: Acts as a protected linker or spacer for solid-phase peptide synthesis (SPPS) to introduce specific functionalities.
• Polymer Chemistry: Employed as a monomer or cross-linking agent for creating functionalized polymers and hydrogels with tailored properties.
• Proteomics Research: Used for site-specific protein labeling and the development of chemical probes to study protein function and interactions.
• Diagnostic Reagent Development: Incorporated into the design of contrast agents, biosensors, and other diagnostic tools.

Basic Information

Product Name	Propargyl-Peg1-Ch2Cootbu
CAS No.	1338564-52-5
Molecular Formula	C11H18O4
Molecular Weight	214.26 g/mol
Synonyms	2-[2-(2-Prop-2-ynoxyethoxy)ethoxy]acetic acid tert-butyl ester; Propargyl-PEG1-CH2COOH-tBu; tert-Butyl 2-[2-(2-prop-2-ynoxyethoxy)ethoxy]acetate; Propargyl-O-PEG1-CH2COOtBu; 2,5,8-Trioxa-11-dodecynoic acid, 12-tert-butyl ester; Propargyl-PEG1-t-butyl ester; Alkyne-PEG1-acid-tBu; Propargyl PEG1 tert-butyl acetate
EINECS	Contact for details

Quality Control

Our Propargyl-Peg1-Ch2Cootbu is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.