Description

5-Amino-2-Fluoro-Benzeneacetic Acid Methyl Ester Hcl CAS NO 1338367-30-8 is a high-purity, functionalized aromatic ester hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of an amino group and a fluorine atom on the phenyl ring, enabling precise molecular modifications. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs) and other complex organic molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in fluorinated pharmaceutical chemistry.
• Agrochemical Synthesis: Building block for creating advanced, fluorinated pesticides and herbicides with enhanced biological activity.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate for synthesizing functional polymers and advanced organic electronic materials.
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) in fluorinated aromatic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	5-Amino-2-Fluoro-Benzeneacetic Acid Methyl Ester Hcl
CAS No.	1338367-30-8
Molecular Formula	C9H11FNO2·HCl
Molecular Weight	219.65 (Free base) / 256.11 (HCl salt)
Synonyms	Methyl 2-(5-Amino-2-fluorophenyl)acetate hydrochloride; 2-(5-Amino-2-fluorophenyl)acetic acid methyl ester hydrochloride; 5-Amino-2-fluorobenzeneacetic acid methyl ester hydrochloride; Methyl (5-amino-2-fluorophenyl)acetate HCl; 1338367-30-8; 5-Amino-2-fluoro-α-toluic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Fluoro-Benzeneacetic Acid Methyl Ester Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.