Description

Ethyl 1-(4-(Trifluoromethoxy)Phenyl)Cyclopropanecarboxylate is a high-value, synthetically versatile organic compound featuring a cyclopropane ring and a trifluoromethoxy phenyl group. This unique structure makes it a critical advanced pharmaceutical intermediate for the development of novel active ingredients. It is primarily sought by R&D chemists and process development teams in the pharmaceutical and agrochemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic materials with specific optical or electronic properties.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create novel chiral ligands or metal-organic frameworks (MOFs) for asymmetric catalysis.
• Chemical Biology Probe: Utilized as a core scaffold for designing molecular probes to study enzyme function and biological pathways in drug discovery.

Basic Information

Product Name	Ethyl 1-(4-(Trifluoromethoxy)Phenyl)Cyclopropanecarboxylate
CAS No.	1338247-55-4
Molecular Formula	C13H13F3O3
Molecular Weight	274.24 g/mol
Synonyms	Ethyl 1-[4-(trifluoromethoxy)phenyl]cyclopropanecarboxylate; 1-(4-(Trifluoromethoxy)phenyl)cyclopropanecarboxylic Acid Ethyl Ester; Cyclopropanecarboxylic acid, 1-[4-(trifluoromethoxy)phenyl]-, ethyl ester; Ethyl 1-(4-(trifluoromethoxyl)phenyl)cyclopropanecarboxylate
EINECS	Contact for details

Quality Control

Our production of Ethyl 1-(4-(Trifluoromethoxy)Phenyl)Cyclopropanecarboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 aligned practices for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.