Description

Thietane-3-Carbonitrile is a specialized heterocyclic organic compound featuring a four-membered thietane ring fused with a nitrile functional group. This unique molecular architecture makes it a valuable and versatile chemical intermediate for advanced synthesis in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, complex natural product analogs, and functional materials. The compound's reactivity is leveraged in ring-opening and cycloaddition reactions to construct more complex sulfur- and nitrogen-containing scaffolds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides with unique modes of action.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Science: Employed in the research of specialty polymers and high-performance materials with specific thermal or chemical resistance.
• Chemical Biology Probes: Useful for synthesizing activity-based probes to study enzyme function and metabolic pathways.
• Fine Chemical Synthesis: Intermediate for producing complex organic molecules in custom synthesis and contract manufacturing.

Basic Information

Product Name	Thietane-3-Carbonitrile
CAS No.	1337882-54-8
Molecular Formula	C4H5NS
Molecular Weight	99.15 g/mol
Synonyms	3-Thietanecarbonitrile; Thietane-3-carbonitrile; 3-Cyanothietane; Tetrahydrothiophene-3-carbonitrile (incorrect but common misnomer); 1-Thia-3-azacyclobutane-3-carbonitrile; 3-Thiacyclobutanecarbonitrile
EINECS	Contact for details

Quality Control

Our Thietane-3-Carbonitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports development from milligram to kilogram scale with full traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.