Description

Benzenamine, N,n-Bis[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-3,5-Bis(Trifluoromethyl)- is a sophisticated, high-value boronic ester derivative of an aniline core, designed for advanced synthetic applications. This compound matters as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecules for high-performance materials. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and organic electronics industries, where its unique structure facilitates the development of novel active ingredients and functional materials. The CAS number for this compound is 1336876-64-2.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key arylboronate ester coupling partner for the synthesis of biaryl structures in pharmaceutical intermediates and advanced materials.
• Pharmaceutical Research & Development: Used as a versatile building block for creating novel drug candidates, particularly those requiring complex, fluorinated aromatic systems.
• Agrochemical Synthesis: Employed in the development of new generation pesticides and herbicides that benefit from the stability and reactivity of the boronate ester group.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport materials or host materials in OLED devices, leveraging the electron-deficient trifluoromethyl groups.
• Polymer Chemistry: Incorporated into monomers for the synthesis of specialty polymers with tailored electronic or thermal properties.
• Ligand Synthesis for Catalysis: Utilized to construct complex nitrogen-containing ligands for transition metal catalysts.
• Material Science Research: Applied in the development of covalent organic frameworks (COFs) or other porous materials due to its rigid, multi-functional structure.
• Chemical Biology & Probe Development: Functions as a handle for bioconjugation or as a core structure for fluorescent probes and sensors.

Basic Information

Product Name	Benzenamine, N,n-Bis[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-3,5-Bis(Trifluoromethyl)-
CAS No.	1336876-64-2
Molecular Formula	C34H38B2F6N1O4
Molecular Weight	652.29 g/mol
Synonyms	N,N-Bis[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3,5-bis(trifluoromethyl)aniline; 3,5-Bis(trifluoromethyl)-N,N-bis[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]benzenamine; Bis(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)(3,5-bis(trifluoromethyl)phenyl)amine; Arylboronate Ester Aniline Derivative; Borylation Product of 3,5-Bis(trifluoromethyl)-N,N-bis(4-bromophenyl)aniline
EINECS	Contact for details

Quality Control

Our Benzenamine, N,n-Bis[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-3,5-Bis(Trifluoromethyl)- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.