Description

Benzonitrile, 4-(3S)-3-Piperidinyl- CAS NO 1336417-30-1 is a high-purity chiral organic intermediate featuring a benzonitrile core substituted with a (3S)-3-piperidinyl group. This compound is of significant value in pharmaceutical research and development, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for constructing complex molecules with specific stereochemical requirements.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly in central nervous system (CNS) and oncology drug candidates.
• Chemical Synthesis Building Block: Used in organic synthesis for constructing complex molecular architectures via reactions involving the nitrile and piperidine functional groups.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis.
• Agrochemical Research: Employed in the discovery and synthesis of advanced crop protection chemicals with specific activity profiles.
• Academic and Institutional Research: Utilized in university and research institute laboratories for methodological studies and the exploration of new chemical spaces.

Basic Information

Product Name	Benzonitrile, 4-(3S)-3-Piperidinyl-
CAS No.	1336417-30-1
Molecular Formula	C12H14N2
Molecular Weight	186.26 g/mol
Synonyms	4-[(3S)-3-Piperidinyl]benzonitrile; (S)-4-(Piperidin-3-yl)benzonitrile; 4-((S)-Piperidin-3-yl)benzonitrile; 4-(3-Piperidinyl)benzonitrile (S-isomer); 1336417-30-1; Benzonitrile, 4-[(3S)-3-piperidinyl]-; (S)-3-(4-Cyanophenyl)piperidine
EINECS	Contact for details

Quality Control

Our Benzonitrile, 4-(3S)-3-Piperidinyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.