Description

2-(Tributylammonium)Ethyl Methanethiosulfonate Bromide is a specialized quaternary ammonium salt derivative of methanethiosulfonate, a key functional group in bioconjugation and protein chemistry. This compound matters as a versatile reagent for introducing disulfide bonds or thiol-reactive groups into biomolecules and synthetic polymers under controlled conditions. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications such as site-specific protein modification, surface functionalization, and the development of drug delivery systems.

Application

• Bioconjugation Reagent: For the site-specific modification of proteins, peptides, and antibodies to introduce thiol-reactive handles or cleavable disulfide linkages.
• Polymer Functionalization: Used to incorporate reactive thiosulfonate groups into polymer backbones for creating stimuli-responsive or cross-linkable materials.
• Surface Chemistry: Enables the functionalization of gold surfaces, nanoparticles, and other materials for biosensor development and diagnostic assays.
• Chemical Biology Probes: Serves as a key intermediate in synthesizing activity-based probes for studying enzyme function and cellular processes.
• Pharmaceutical Intermediates: Employed in the synthesis of complex drug candidates, particularly those requiring targeted release mechanisms.
• Cross-linking Agent: Facilitates the formation of reversible disulfide bridges in hydrogel formation and biomaterial engineering.

Basic Information

Product Name	2-(Tributylammonium)Ethyl Methanethiosulfonate Bromide
CAS No.	1335200-79-7
Molecular Formula	C15H34BrNO2S2
Molecular Weight	396.46 g/mol
Synonyms	2-(Tributylammonio)ethyl methanethiosulfonate bromide; MTSET-Bu3N; (2-Methanethiosulfonatoethyl)tributylammonium bromide; Tributyl(2-((methylsulfonyl)thio)ethyl)ammonium bromide; MTSEA-tributylammonium salt; Thiol-reactive ammonium salt; S-Methyl methanethiosulfonate tributylammonium derivative
EINECS	Contact for details

Quality Control

Our 2-(Tributylammonium)Ethyl Methanethiosulfonate Bromide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with high-purity research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. Due to its hygroscopic (moisture-sensitive) nature, the container should be sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.