Description

5-[3-(Trifluoromethyl)Phenyl]-3H-1,3,4-Oxadiazol-2-One is a high-value, fluorinated heterocyclic compound belonging to the oxadiazolone class. This specialized intermediate is critical for research and development in advanced organic synthesis, particularly for introducing the trifluoromethylphenyl pharmacophore. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers focused on creating novel active ingredients for agrochemicals and pharmaceuticals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the trifluoromethyl group enhances biological activity and stability.
• Material Science: Acts as a precursor for advanced polymers and liquid crystals with specific optical or electronic properties.
• Organic Synthesis: A versatile reagent for constructing complex heterocyclic frameworks in academic and industrial research settings.
• Chemical Biology: Employed as a probe or linker in the design of enzyme inhibitors and other bioactive molecules.

Basic Information

Product Name	5-[3-(Trifluoromethyl)Phenyl]-3H-1,3,4-Oxadiazol-2-One
CAS No.	1334627-21-2
Molecular Formula	C9H5F3N2O2
Molecular Weight	230.15 g/mol
Synonyms	3-[3-(Trifluoromethyl)phenyl]-1,3,4-oxadiazol-2(3H)-one; 5-(3-Trifluoromethylphenyl)-2-oxo-2,3-dihydro-1,3,4-oxadiazole; 3-(3-Trifluoromethylphenyl)-1,3,4-oxadiazol-2(3H)-one; 5-(α,α,α-Trifluoro-m-tolyl)-1,3,4-oxadiazol-2(3H)-one; 2-Oxo-5-[3-(trifluoromethyl)phenyl]-2,3-dihydro-1,3,4-oxadiazole; 1,3,4-Oxadiazol-2(3H)-one, 5-[3-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Every batch of 5-[3-(Trifluoromethyl)Phenyl]-3H-1,3,4-Oxadiazol-2-One is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are supported by a detailed Certificate of Analysis (COA) that includes data from HPLC, NMR, and mass spectrometry. We adhere to cGMP principles where applicable to meet the stringent requirements of our global pharmaceutical and agrochemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.