Description

4-Isopropanoxy-3-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative, a critical intermediate in modern synthetic chemistry. Its value lies in its enhanced stability and reactivity, making it a superior building block for complex molecule assembly compared to its free acid counterpart. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to construct key molecular frameworks through cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing active pharmaceutical ingredients (APIs), especially those containing trifluoromethyl and aryl ether motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific aryl-boron components for structure-activity optimization.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and semiconductors, where the boronic ester group enables precise molecular architecture.
• Chemical Biology & Probe Synthesis: Utilized to create molecular probes and bioconjugates for studying biological processes and diagnostic applications.

Basic Information

Product Name	4-Isopropanoxy-3-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester
CAS No.	1334607-79-2
Molecular Formula	C₁₆H₂₂BF₃O₃
Molecular Weight	330.15 g/mol
Synonyms	4-(Isopropoxy)-3-(trifluoromethyl)benzeneboronic acid pinacol ester; 3-Trifluoromethyl-4-isopropoxyphenylboronic acid pinacol ester; [4-(Propan-2-yloxy)-3-(trifluoromethyl)phenyl]boronic acid pinacol ester; 4-Isopropoxy-3-trifluoromethylphenylboronic acid pinacol ester; Boronic acid, B-[4-(1-methylethoxy)-3-(trifluoromethyl)phenyl]-, 1,1-dimethylethyl ester; PINACOL [4-ISOPROPOXY-3-(TRIFLUOROMETHYL)PHENYL]BORONATE
EINECS	Contact for details

Quality Control

Our 4-Isopropanoxy-3-(trifluoromethyl)phenylboronic acid pinacol ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this moisture-sensitive material from atmospheric humidity. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.