Description

3-Amino-1,1,1-Trifluoro-2-Methylpropan-2-Ol is a high-value, fluorinated amino alcohol building block. This compound matters for its unique trifluoromethyl group, which imparts desirable properties like metabolic stability and enhanced lipophilicity to target molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for developing fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides where the fluorine moiety improves efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Incorporated into specialty polymers and coatings to modify surface properties and chemical resistance.
• Fluorine Chemistry Research: A valuable building block for exploring new reactions and methodologies in organofluorine chemistry.
• Peptidomimetics: Used in the design and synthesis of fluorinated peptide analogs with improved stability.

Basic Information

Product Name	3-Amino-1,1,1-Trifluoro-2-Methylpropan-2-Ol
CAS No.	1334546-33-6
Molecular Formula	C4H8F3NO
Molecular Weight	143.11 g/mol
Synonyms	2-(Trifluoromethyl)-2-amino-1-propanol; 2-Amino-2-(trifluoromethyl)propan-1-ol; 2-Amino-2-(trifluoromethyl)-1-propanol; 1,1,1-Trifluoro-2-amino-2-methylpropanol; 3-Amino-1,1,1-trifluoro-2-methyl-2-propanol; 2-Methyl-3-amino-1,1,1-trifluoropropan-2-ol; α-(Trifluoromethyl)-β-alanine alcohol derivative
EINECS	Contact for details

Quality Control

Our 3-Amino-1,1,1-Trifluoro-2-Methylpropan-2-Ol is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided and available upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.